Thorax -- eLetters for Roberts et al., 58 (4) 306-310

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Electronic Letters to:

G Roberts, D Newsom, K Gomez, A Raffles, S Saglani, J Begent, P Lachman, K Sloper, R Buchdahl, and A Habel

Intravenous salbutamol bolus compared with an aminophylline infusion in children with severe asthma: a randomised controlled trial
Thorax 2003; 58: 306-310 [Abstract] [Full text] [PDF]

Electronic letters published:

Salbutamol vs aminophylline in severe asthma in children: Florens GA Versteegh (23 May 2003)

Salbutamol vs aminophylline in severe asthma in children

23 May 2003

Florens GA Versteegh,
Paediatrician
GHZ, Gouda, the Netherlands

Send letter to journal:
Re: Salbutamol vs aminophylline in severe asthma in children

florens.versteegh{at}ghz.nl Florens GA Versteegh

Dear Editor

It is indeed a pity that there was no comparison between continuous aminophylline and continuous salbutamol. The authors did not make it very clear why they did not choose this option. The conclusion that there is some favourable outcome with aminophylline is therefore, in my opinion, too strong for the data they present. Another query is: Why did the authors use aminophylline, instead of theofylline, with the risk of provoking an allergy to ethylenediamine?

Reference

(1) Hardy C, Schofield O, George CF: Allergy to aminophylline. Br Med J (Clin Res Ed) 1983 Jun 25;286(6383):2051-2.

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