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Paediatric respiratory syncytial virus infections: rates and risk factors for hospitalisation
Correspondence to:
Dr R Ahmed, ST2, Addenbrookes Hospital, Cambridge, UK; rkia@doctors.org.uk
| The first 150 words of the full text of this article appear below. |
This population-based prospective study set out to establish the rates of respiratory syncytial virus (RSV)-associated paediatric respiratory tract infections in both inpatient and outpatient settings. Cases were identified through the New Vaccine Surveillance Network, a Centre for Disease Control initiative to survey acute respiratory infections in children aged <5 years in three geographically diverse US counties. The study was conducted during November to April between 2000 and 2004.
Nasal and throat swabs were analysed by RT-PCR and culture for RSV and other viruses including influenza, parainfluenza, rhinovirus and metapneumovirus. Of 6225 children with acute respiratory infections identified during the surveillance period, 5067 (81%) were enrolled of which 919 (18%) were RSV-positive; 6% of those were co-infected, most commonly with influenza virus. Three hundred and fifty-five RSV-infected children (39%) were treated in the community or emergency department. Those hospitalised (61%) were more likely to be under 6 months of
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