MISCELLANEOUS
Pulmonary puzzle
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From question on page 10.1136/thx.2007.088237
The bronchial biopsy showed normal columnar epithelium along with metaplastic squamous epithelium. Below the mucosa there were nodules of hyaline cartilage showing focal calcification and cancellous bone with thin trabeculae (fig 1D, arrow) and areas of fatty marrow (fig 1D, arrowhead). These features are diagnostic of "tracheobronchopathia osteochondroplastica".
Tracheobronchopathia osteochondroplastica (TO) is a rare benign condition of unknown aetiology involving the tracheobronchial tree and was first described in 1857. It usually affects adults with equal gender distribution. TO is characterised by the development of multiple osseous and cartilaginous nodules in the submucosa of the trachea and the main bronchi. Typically, these nodules develop in the cartilaginous anterior and lateral parts of the trachea with sparing of the posterior part. The precise incidence and prevalence of this disorder is unknown but autopsy reporting suggests 3/1000. TO may be an incidental diagnosis or patients may
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Thorax 2008 63: 128.[Extract] [Full Text] [PDF]
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