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TB epidemiology
THE OUTCOME OF A COHORT OF TUBERCULIN POSITIVE, PREDOMINANTLY SOUTH ASIAN, NEW ENTRANTS AGED 16–34 TO THE UK: BLACKBURN 1989–2001
I. W. Choudry¹, L. P. Ormerod²,³. ¹Central Lancs PCT; ²Royal Blackburn Hospital; ³University of Central Lancs, UK

Background: The incidence of TB in new entrants aged 16–34 with positive tuberculin tests but normal chest x ray/examination after initial entry is uncertain and has been estimated for the NICE economic appraisal of new entrant screening.

Methods: New entrants aged 16–34 years predominantly from South Asia with tuberculin tests inappropriately positive for BCG history from 1989–2001 were studied and matched to the local notification database to July 2006.

Results: 479 entrants with normal chest x rays were identified. Median age was 24.0 years, 19% had prior BCG. The observation time was 4668.5 years. 49 developed clinical TB up to July 2006. The median detection of TB was 47 months, 75% by 79 months and none after 156 months. The incidence density of cases was 1050/100 000 person years (95% . . . [Full text of this article]