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Evolution and science, progress and change

Correspondence to:
Correspondence to:
Dr Frank C Detterbeck
Thoracic Surgery, Yale University School of Medicine, New Haven, Connecticut 06520-8062, USA; frank.detterbeck@yale.edu

The first 150 words of the full text of this article appear below.

Staging of non-small cell lung cancer (NSCLC) has undergone a significant evolution, from plain chest radiographs to anatomical imaging, invasive techniques and, most recently, metabolic imaging using positron emission tomography (PET) scans. Even the literature regarding PET imaging has undergone significant evolution. Initial reports were characterised by compelling yet anecdotal images. This was followed by approximately 10 years of studies showing that mediastinal staging by PET was superior to computed tomography (CT) which, of course, was not surprising because CT had already been shown to be notoriously misleading in many situations. Eventually authors began addressing the clinically more relevant question of whether PET can replace invasive mediastinal staging. The article by Tournoy and colleagues¹ in this issue of Thorax illustrates how far we have come (see page 696). Not only does this study use the most sophisticated technology—an integrated PET/CT scanner—but, more importantly, the authors . . . [Full text of this article]

Relevant Article

Integrated FDG-PET/CT does not make invasive staging of the intrathoracic lymph nodes in non-small cell lung cancer redundant: a prospective study

K G Tournoy, S Maddens, R Gosselin, G Van Maele, J P van Meerbeeck, and A Kelles
Thorax 2007 62: 696-701. [Abstract] [Full Text] [PDF]