HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER		Author Keyword(s) Vol Page [Advanced]

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this link to a friend Similar articles in this journal Similar articles in PubMed Add article to my folders Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Southern, K. W Search for Related Content PubMed PubMed Citation Articles by Southern, K. W Topic Collections Relevant Article

Acute renal failure in people with cystic fibrosis

Correspondence to:
Correspondence to:
Dr Kevin W Southern
Institute of Child Health, University of Liverpool, Royal Liverpool Children’s Hospital, Liverpool L12 2AP, UK; kwsouth@liv.ac.uk

The first 150 words of the full text of this article appear below.

The putative gene in cystic fibrosis (CF) encodes a protein, cystic fibrosis transmembrane conductance regulator (CFTR), which has an important role in transepithelial salt transport.¹ The major organ affected in CF is the lung, with remorseless and intense chronic airway infection resulting from disabled clearance of dehydrated airway surface liquid.² Airway inflammation leading to end stage lung damage is associated with respiratory morbidity and early death. The outlook for people with CF has improved considerably with a proactive approach to treatment of airway infection as one of the cornerstones of its management. Recent data from the US CF registry suggest a continuing improvement in median predicted survival to over 35 years (http://www.cff.org/research/2006NACFC/Plenary III). With an improving outlook, perspectives have changed and expectations of people with CF and their carers have broadened. A survey of acute renal failure (ARF) in patients with CF . . . [Full text of this article]

Relevant Article

Survey of acute renal failure in patients with cystic fibrosis in the UK

Carol Bertenshaw, Alan R Watson, Sarah Lewis, and Alan Smyth
Thorax 2007 62: 541-545. [Abstract] [Full Text] [PDF]