EDITORIAL
Chemokines in severe exacerbations of asthma
The laws of attraction: chemokines, neutrophils and eosinophils in severe exacerbations of asthma
Department of Cardiothoracic and Vascular Sciences, Section of Respiratory Diseases, University of Padova, Italy
Correspondence to:
Correspondence to:
Marina Saetta
Divisione di Pneumologia, Dipartimento di Scienze Cardiologiche, Toraciche e Vascolari, Università degli Studi di Padova, Via Giustiniani 3, 35128 Padova, Italy; marina.saetta@unipd.it
A possible new therapeutic strategy for preventing exacerbations
| The first 150 words of the full text of this article appear below. |
Asthma is an extremely common illness which affects an estimated 300 million people of all ages and ethnic backgrounds worldwide with significant costs for healthcare systems.1 The clinical course of the disease is characterised by acute episodes of worsening of symptoms and decrease in lung function known as exacerbations. Prevention of exacerbations has been the goal of most therapeutic interventions developed so far because exacerbations seriously affect the quality of life of patients and their families.2 The clinical presentation of asthma exacerbations may be extremely heterogeneous; they can be rapid in onset or occur more gradually. The severity of asthma exacerbations is also extremely variable, ranging from mild episodes to severe attacks which result in respiratory failure and may ultimately lead to death.
Airway inflammation is a characteristic feature consistently present in patients with asthma from the early stages in children3 to elderly people.4
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
Relevant Articles
- Airwaves
- Wisia Wedzicha
Thorax 2007 62: 465.[Extract] [Full Text] [PDF]
- Bronchial mucosal inflammation and upregulation of CXC chemoattractants and receptors in severe exacerbations of asthma
- Yusheng Qiu, Jie Zhu, Venkata Bandi, Kay K Guntupalli, and Peter K Jeffery
Thorax 2007 62: 475-482.[Abstract] [Full Text] [PDF]
- Full Text
- Full Text (PDF)
- Alert me when this article is cited
- Alert me if a correction is posted
- Citation Map
Services
- Email this link to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
