EDITORIAL
Cystic fibrosis/bronchiectasis exacerbations
Pulmonary exacerbations in cystic fibrosis and bronchiectasis
1 Respiratory Medicine Research Group, Queens University of Belfast and Adult CF Centre Belfast City Hospital, Belfast BT9 7AB, UK
2 Adult Cystic Fibrosis Centre and School of Medicine, University of Queensland, The Prince Charles Hospital, Brisbane 4032, Australia
Correspondence to:
Correspondence to:
Professor J S Elborn
Adult CF Centre Belfast City Hospital, Belfast BT9 7AB, UK; Stuart.Elborn@bch.n-i.nhs.uk
A series of papers reviewing pulmonary exacerbations in CF and bronchiectasis
| The first 150 words of the full text of this article appear below. |
In the current (see page 360) and forthcoming issues of Thorax we are publishing a series examining current practice and evidence of the epidemiology and pathogenesis, prevention and treatment of pulmonary exacerbations in patients with cystic fibrosis (CF) and bronchiectasis.1–4 This follows on from a recent series examining aspects of exacerbations of chronic obstructive pulmonary disease and asthma. These reviews involved authors from Australia, USA and the UK, and each has considered the topics from both a paediatric and adult perspective. Several themes emerge in these reviews, including: (1) the challenges of diagnostic precision of definitions of respiratory exacerbations; (2) the need to develop new and/or novel endpoints for therapeutic trials for the treatment of exacerbations; and (3) the urgent need for multicentre studies to investigate both preventive and therapeutic interventions for patients with CF and bronchiectasis.
Goss and Burns highlight recent studies which have
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