EDITORIAL
Asthma-specific QoL
Further evidence that the wealthier are healthier: negative life events and asthma-specific quality of life
Correspondence to:
Correspondence to:
Dr R J Wright
Channing Laboratory, Brigham & Women’s Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA;rosalind.wright@channing.harvard.edu
Association between psychological stress and asthma expression and morbidity
| The first 150 words of the full text of this article appear below. |
In this issue of Thorax, Archea et al1(see p 139) add to the growing number of studies linking psychological stress to asthma expression and morbidity. To date, studies have reported an association between various measures of life stress and both the onset of asthma or precedent phenotypes2,3 and exacerbations of established disease.4–6 Hypothesised mechanisms underlying the association between stress and asthma expression implicate reciprocal relationships between neural, hormonal and immunological pathways that have been extensively reviewed previously.7,8 Evidence demonstrating that psychological stress influences the expression of inflammatory cytokine patterns in patients with asthma or those at risk of developing the disease supports these theories.9,10 Others have shown that physiological changes, including neuroimmune and genetic processes, may lead to differential responses to therapeutic interventions for asthma and atopic disorders.11,12
The current work by Archea et al1 underscores that psychological factors may also be more indirect, albeit
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- Negative life events and quality of life in adults with asthma
- C Archea, I H Yen, H Chen, M D Eisner, P P Katz, U Masharani, E H Yelin, G Earnest, and P D Blanc
Thorax 2007 62: 139-146.[Abstract] [Full Text] [PDF]
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