LUNG ALERT
Asbestos and man-made vitreous fibres may not currently contribute to the burden of lung cancer
Research Registrar, London Chest Hospital, London, UK; swapnamandal@hotmail.com
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Carel R, Olsson AC, Zaridze D, et al. Occupational exposure to asbestos and man-made vitreous fibre and risk of lung cancer: a multicentre case-control study in Europe. Occup Environ Med 2007;64:502–08.
Asbestos is an environmental carcinogen and exposure has been linked with the development of lung cancer. The use of asbestos has been partially replaced by man-made vitreous fibres (MMVF). The aim of this case–control study was to quantify the contribution of asbestos and MMVF to the burden of lung cancer in men, while controlling for confounding factors.
Over 4000 participants in seven countries were asked about smoking, lifestyle factors and all jobs held for >1 year. For specific occupations the likelihood of exposure to MMVF or asbestos and the frequency and intensity of exposure was assessed.
Lung cancer risk following asbestos exposure differed between countries. For central and eastern Europe the odds ratio
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