EDITORIAL
High-grade lesion
High-grade lesion: what does it tell us?
Correspondence to:
Correspondence to:
Dr E S Edell
Mayo Clinic, First Avenue SW, Rochester, MN 55902, USA; eedell@mayo.edu
Surveillance programmes for patients with high-grade lesions, which may progress to invasive cancer, will require tissue archives for histology and cooperation and collaboration of participating centres
| The first 150 words of the full text of this article appear below. |
Lung cancer remains the leading cause of death due to cancer in both men and women in several countries. Most patients with lung cancer present with non-specific symptoms such as cough, dyspnoea or haemoptysis and have late-stage disease at the time of diagnosis. Treatment strategies are thus often palliative rather than curative. Early detection trials using routine chest roentgenograms and sputum cytology have shown that cancers can be detected at earlier stages but the overall mortality from lung cancer was not improved. With new technology developments, such as low-dose computed tomography and fluorescence bronchoscopy, comes new hope that early detection may in fact change this pattern.
Squamous cell carcinoma, although no longer the most common type of lung cancer, remains a major problem, accounting for 17–29% of lung cancers.1 Studies on sputum cytology showed that 11% of individuals with moderate dysplasia and 19–46% with severe dysplasia progressed to
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
Relevant Article
- Surveillance for the detection of early lung cancer in patients with bronchial dysplasia
- Philip Jeremy George, Anindo K Banerjee, Catherine A Read, Caoihme O’Sullivan, Mary Falzon, Francesco Pezzella, Andrew G Nicholson, Penny Shaw, Geoff Laurent, and Pamela H Rabbitts
Thorax 2007 62: 43-50.[Abstract] [Full Text] [PDF]
Services
- Email this link to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
-
Screening (oncology)
-
Cardiothoracic surgery
-
Lung cancer (oncology)
-
Lung cancer (respiratory medicine)
-
Lung neoplasms
- Relevant Article
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
