EDITORIAL
Glycaemic control in COPD
Tight glycaemic control in acute exacerbations of COPD
Adult Intensive Care Unit, Royal Brompton Hospital, London SW3 6LY, UK
Correspondence to:
Correspondence to:
Professor T W Evans
Adult Intensive Care Unit, Royal Brompton Hospital, Sydney Street, London SW3 6LY, UK; t.evans@rbht.nhs.uk
A new standard of care?
Keywords: hyperglycaemia; chronic obstructive pulmonary disease; insulin
| The first 150 words of the full text of this article appear below. |
It is now clear that hyperglycaemia of even short duration can be associated with adverse outcome in the acutely ill. Thus, the hyperglycaemic state has been associated with increased mortality in patients undergoing cardiothoracic surgery or suffering acute myocardial infarction, in victims of major trauma and those sustaining brain injury, and in association with community acquired pneumonia.1–5 In this issue of Thorax Baker and colleagues extend this list, having performed a retrospective analysis of outcome in patients admitted to hospital with an acute exacerbation of chronic obstructive pulmonary disease (COPD).6 Multivariate analysis revealed that hyperglycaemia held more adverse prognostic significance even than spirometry. Not surprisingly, the authors propound the hypothesis that rigorous glycaemic control should improve mortality and/or reduce the length of hospital stay in this patient population which is so commonly encountered during the acute general medical take. To this end, they propose that a
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Thorax 2006 61: 275.[Extract] [Full Text] [PDF]
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