Airwaves
| The first 150 words of the full text of this article appear below. |
Pneumococcal disease is a major public health problem and is important in patients with chronic obstructive pulmonary disease (COPD). Although the pneumococcal polysaccharide vaccine (PPV) has been available for some time, there has been debate as to its effectivesness, particularly in the elderly and other at risk groups. In this months Thorax we publish a randomised controlled trial by Alfageme and colleagues on the use of the 23-valent PPV in COPD patients, with community acquired pneumonia (CAP) as the primary outcome. Overall, there were no significant differences in CAP between the intervention and non-intervention groups and the efficacy of the vaccine in the whole group was 24%. However, in patients under 65 years and in those with more severe airflow obstruction, PPV was effective in preventing CAP. The authors conclude that younger COPD patients with more severe disease need vaccination. In the accompanying editorial Hall discusses the UK policy of
Relevant Articles
- Polysaccharide pneumococcal vaccination: new evidence
- A J Hall
Thorax 2006 61: 183-184.[Extract] [Full Text] [PDF]
- Think globally, breathe locally
- R J Delfino
Thorax 2006 61: 184-185.[Extract] [Full Text] [PDF]
- How best to determine optimal nasal CPAP in patients with OSAH?
- A Mulgrew and J A Fleetham
Thorax 2006 61: 186-187.[Extract] [Full Text] [PDF]
- COPD exacerbations · 2: Aetiology
- E Sapey and R A Stockley
Thorax 2006 61: 250-258.[Abstract] [Full Text] [PDF]
- Locally generated particulate pollution and respiratory symptoms in young children
- N Pierse, L Rushton, R S Harris, C E Kuehni, M Silverman, and J Grigg
Thorax 2006 61: 216-220.[Abstract] [Full Text] [PDF]
- Clinical efficacy of anti-pneumococcal vaccination in patients with COPD
- I Alfageme, R Vazquez, N Reyes, J Muñoz, A Fernández, M Hernandez, M Merino, J Perez, and J Lima
Thorax 2006 61: 189-195.[Abstract] [Full Text] [PDF]
- Comparison of three ways to determine and deliver pressure during nasal CPAP therapy for obstructive sleep apnoea
- S D West, D R Jones, and J R Stradling
Thorax 2006 61: 226-231.[Abstract] [Full Text] [PDF]
- Evaluation of airway inflammation by quantitative Th1/Th2 cytokine mRNA measurement in sputum of asthma patients
- E Truyen, L Coteur, E Dilissen, L Overbergh, L J Dupont, J L Ceuppens, and D M A Bullens
Thorax 2006 61: 202-208.[Abstract] [Full Text] [PDF]
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
