EDITORIAL
Emphysema in COPD
Emphysema in COPD: consequences and causes
Correspondence to:
Correspondence to:
Dr G M Turino
Department of Medicine, St Luke’s-Roosevelt Hospital Center, 1000 Tenth Avenue, New York, NY10019, USA; gmt1@columbia.edu
There is still much to be learned about the cellular and cytokine reactions of specific phenotypes in COPD
Keywords: chronic obstructive pulmonary disease; emphysema; biological markers; outcomes
| The first 150 words of the full text of this article appear below. |
The current definition of chronic obstructive pulmonary disease (COPD), which has been established by the Global Initiative on Obstructive Lung Disease (GOLD)1 and also adopted, in large part, by the American Thoracic Society and the European Respiratory Society,2 is that COPD is a "preventable and treatable disease state characterized by airflow limitation that is not fully reversible". This definition has the virtue of simplicity and clinical applicability but necessarily includes patients with widely varying clinical phenotypes and pathogenic mechanisms. The paper by Boschetto et al3 in this issue of Thorax focuses on the role of radiologically identified pulmonary emphysema in a group of patients diagnosed with COPD on the basis of their presenting clinical state and separated into groups for comparison between those with and without radiologically identified emphysema.
Patient selection began with 50 individuals with COPD who then underwent computed tomographic (CT) scanning with a third
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