EDITORIAL

Creatine supplementation in COPD

Creatine supplementation as an exercise performance enhancer for patients with COPD? An idea to run with

T L Griffiths¹, D Proud²

¹ Wales College of Medicine, Cardiff University, Llandough Hospital, Penarth CF64 2XX, UK
² Pulmonary Rehabilitation Unit, Llandough Hospital, Penarth CF64 2XX, UK

Correspondence to:
Correspondence to:
Dr T L Griffiths
Wales College of Medicine, Cardiff University, Llandough Hospital, Penarth, CF64 2XX, UK; griffithstl@cf.ac.uk

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Creatine supplementation may enhance pulmonary rehabilitation in patients with COPD, but larger trials are needed

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Keywords: creatine; pulmonary rehabilitation; chronic obstructive pulmonary disease; exercise tolerance; fat-free mass; quality of life

The first 150 words of the full text of this article appear below.

Multidisciplinary pulmonary rehabilitation now has an established place in the management of chronic disabling respiratory diseases, particularly chronic obstructive pulmonary disease (COPD).¹ Rehabilitation is being taken up widely on the strength of the accumulated evidence. While the effectiveness of rehabilitation is accepted, there is still considerable interest in refining and researching the individual modalities of treatment that make up the multidisciplinary intervention.

Exercise training is a key component of an effective pulmonary rehabilitation programme. In recent years a number of approaches have been taken in an effort to enhance the effectiveness of physical training, particularly for more severely disabled patients who may have reduced muscle bulk and whose baseline exercise capacity is particularly low. Broadly, strategies have either concentrated on acute interventions that enable subjects to train at higher intensity or have focused on altering underlying skeletal muscle functioning. An example of the former approach is . . . [Full text of this article]

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• Deacon, S. J., Vincent, E. E., Greenhaff, P. L., Fox, J., Steiner, M. C., Singh, S. J., Morgan, M. D. (2008). Randomized Controlled Trial of Dietary Creatine as an Adjunct Therapy to Physical Training in Chronic Obstructive Pulmonary Disease. Am. J. Respir. Crit. Care Med. 178: 233-239 [Abstract] [Full Text]