© 2005 BMJ Publishing Group Ltd & British Thoracic Society
EDITORIAL
Tuberculin testing
Tuberculin testing, BCG and tuberculosis today
Correspondence to:
Correspondence to:
Dr J Moore-Gillon
Department of Respiratory Medicine, St Bartholomew’s and Royal London Hospitals, London EC1A 7BE, UK; john.moore-gillon@bartsandthelondon.nhs.uk
Little progress has been made in the last 50 years
Keywords: BCG vaccination; annual risk; tuberculosis; tuberculin testing; children
| The first 150 words of the full text of this article appear below. |
Tuberculosis is not simply a problem hanging over from the past—it is a growing challenge—but what are the risks of acquiring tuberculosis infection in childhood, and how should those risks be assessed?
In this issue of Thorax Leung and colleagues1 analyse the results of tuberculin skin testing in over 21 000 children in Hong Kong aged 6–9 years between October 1999 and February 2000. 99% of the children had received BCG vaccination in the neonatal period. The authors used three different approaches to the data to estimate the subsequent annual risk of tuberculous infection. In broad terms, one approach used the size of the tuberculin response to assess whether infection had occurred, using a cut off point of 
10 mm induration after skin testing with one unit of tuberculin. They then used age (which equals the number of years each child had been at risk of infection) to
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