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Thorax 2004;59:361-363; doi:10.1136/thx.2003.020040
Copyright © 2004 BMJ Publishing Group Ltd & British Thoracic Society.
Thorax 2004;59:361-363
© 2004 BMJ Publishing Group Ltd & British Thoracic Society

EDITORIAL

Sleep disordered breathing and stroke

Sleep disordered breathing and the outcome of stroke

G J Gibson

Correspondence to:
Correspondence to:
Professor G J Gibson
Department of Respiratory Medicine, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK; g.j.gibson@ncl.ac.uk


Patients with OSA not only have an increased risk of stroke, but also a higher mortality and greater disability after stroke

Keywords: sleep disordered breathing; obstructive sleep apnoea; stroke; outcome

Abbreviations: AHI, apnoea-hypopnoea index; OSA, obstructive sleep apnoea; SDB, sleep disordered breathing; TIA, transient ischaemic attack

The first 150 words of the full text of this article appear below.

Interest in abnormal breathing after stroke has a long history dating back at least to the observations of John Cheyne in 1818.1 In recent years this interest has been reawakened by a number of publications on the relations between sleep disordered breathing (SDB) and stroke. These studies have been of two main types—those investigating the possible increased risk of stroke in individuals with obstructive sleep apnoea (OSA) and those reporting a high prevalence of SDB after stroke and its possible effects on residual disability and mortality. Unravelling the direction of causality—that is, whether OSA causes stroke or stroke causes OSA—has proved challenging.2–5

OSA AND RISK OF STROKE

Most of the evidence on the risk of stroke associated with OSA is circumstantial and is based on case-control studies in which a history of snoring, with or without other features suggestive of OSA, is compared in patients with stroke and matched controls.6–11 . . . [Full text of this article]


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This article has been cited by other articles:

  • McNicholas, W. T., Bonsignore, M. R., the Management Committee of EU COST ACTION B26, (2007). Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities. Eur Respir J 29: 156-178 [Abstract] [Full Text]  
  • Gibson, G.J. (2005). Obstructive sleep apnoea syndrome: underestimated and undertreated. Br Med Bull 72: 49-65 [Abstract] [Full Text]  

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