© 2004 BMJ Publishing Group Ltd & British Thoracic Society
EDITORIAL
Smoking, cadmium, and emphysema
Smoking, cadmium, and emphysema
Correspondence to:
Correspondence to:
D J Hendrick
Department of Respiratory Medicine, Royal Victoria Infirmary, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 4LP, UK; d.j.hendrick@ncl.ac.uk
Does cadmium contribute to the development of smoking induced emphysema?
Keywords: cadmium; smoking; lung function; chronic obstructive pulmonary disease
| The first 150 words of the full text of this article appear below. |
Most respiratory physicians recognise that chronic exposure to respirable cadmium in the workplace may lead to emphysema. What may come as a surprise is that cadmium is a constituent of tobacco and hence cigarette smoke, and so is inhaled outside the workplace by all smokers. The question arises whether inhaled cadmium may contribute to, or even be the principal cause of, smoking induced emphysema.
Mannino and colleagues have taken advantage of the Third US National Health and Nutritional Examination Survey (NHANES III) to investigate the matter, since it allowed them to compare creatinine adjusted urinary cadmium levels with spirometric measurements in as many as 16 024 subjects, representative of the adult US population. Their findings are presented in this issue of Thorax.1 Not only was there an increasing trend in urinary cadmium levels from never, through former, to current smokers, but among the current and
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Thorax 2004 59: 181.[Extract] [Full Text] [PDF]
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