© 2004 BMJ Publishing Group Ltd & British Thoracic Society
EDITORIAL
NIV in acute exacerbations of COPD
Non-invasive ventilation in acute exacerbations of COPD: what happens after hospital discharge?
Correspondence to:
Correspondence to:
Dr M W Elliott
Consultant Respiratory Physician, St Jamess University Hospital, Beckett Street, Leeds LS9 7TF, UK; mwelliott@doctors.org.uk
The role of domiciliary NIV in patients with COPD
Keywords: chronic obstructive pulmonary disease; respiratory failure; non-invasive ventilation; outcome; survival
| The first 150 words of the full text of this article appear below. |
Now that non-invasive ventilation (NIV) is well established in clinical practice, particularly for chronic obstructive pulmonary disease (COPD),1,2 it is likely that more patients will survive an acute exacerbation, especially in countries such as the UK where comparatively few patients with COPD are ventilated invasively. However, it is possible that some patients are now just being saved for a future life of poor quality at home, punctuated by recurrent admissions to hospital because their respiratory reserve is so marginal that even trivial exacerbations are sufficient to provoke life threatening ventilatory failure.
Before NIV was widely available, Connors et al3 showed that hypercapnia during an admission with an acute exacerbation of COPD was a poor prognostic indicator. In a prospective study of a cohort of 1016 patients who were admitted with an exacerbation of COPD and a PaCO2 of 50 mm Hg (6.6 kPa)
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