© 2004 BMJ Publishing Group Ltd & British Thoracic Society
EDITORIAL
Failure of empirical treatment for CAP
Identifying failure of empirical treatment for pneumonia: vigilance and common sense
Correspondence to:
Correspondence to:
Dr W-S Lim
Respiratory Medicine, David Evans Research Centre, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK; wlim2@ncht.trent.nhs.uk
Some progress in identifying the risk factors associated with treatment failure in CAP
Keywords: community acquired pneumonia; antimicrobial treatment; failure; mortality; risk factors; prognosis
| The first 150 words of the full text of this article appear below. |
In patients with community acquired pneumonia (CAP), clinical and radiological features at the time of presentation do not predict the microbiological aetiology with any certainty.1 Initial treatment is therefore usually empirical and directed by the severity of the illness at the time of presentation. A large number of studies have been conducted over the last 10 years to determine prognostic factors in CAP. In turn, clinical prediction rules based on a number of key prognostic factors have been developed, such as the pneumonia severity index (PSI) and the CURB-65 score, and incorporated into CAP management guidelines.2–6 Most of these CAP severity studies, and the resulting prediction rules, use mortality as the main outcome measure. However, mortality is not the only clinically important outcome. In this issue of Thorax, Menéndez and colleagues report on a large observational study of the risk factors related to
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Thorax 2004 59: 913.[Extract] [Full Text] [PDF]
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