© 2002 Thorax
EDITORIAL
Cystic fibrosis
Psychological consequences of segregation resulting from chronic Burkholderia cepacia infection in adults with CF
Correspondence to:
Correspondence to:
Dr A J A Duff, Department of Clinical & Health Psychology & Regional CF Unit, St James's University Hospital, Leeds LS9 7TF, UK;
a.j.a.duff@leeds.ac.uk
Patients with CF segregated because of Burkholderia cepacia infection must be helped to assemble coherent structures for social relationships if they are to adapt successfully to such management.
Keywords: cystic fibrosis; psychology; Burkholderia cepacia
| The first 150 words of the full text of this article appear below. |
In 1997 the median life expectancy for individuals with cystic fibrosis (CF) was 31.5 years in the UK1 and it has been suggested that those born today can expect to live well into their mid 40s.2 However, there is huge variability in the physical condition of adults with CF. While malabsorption, osteoporosis, diabetes, and liver failure all contribute to incapacity, lung disease is the main cause of morbidity and mortality. Some patients have near normal levels of lung function. Others, however, are debilitated by dyspnoea and dependent on oxygen.
Lung disease in CF is primarily due to the consequences of infection. In the first decade of life Staphylococcus aureus and Haemophilus influenzae are the predominant organisms in sputum, while in older children and adults Pseudomonas aeruginosa is most common.3 In the past 15 years some CF centres have had epidemics of Burkholderia cepacia infection. Although patients respond to
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Abbott, J
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6: 31-41
[Abstract] -
Loutet, S. A., Flannagan, R. S., Kooi, C., Sokol, P. A., Valvano, M. A.
(2006). A Complete Lipopolysaccharide Inner Core Oligosaccharide Is Required for Resistance of Burkholderia cenocepacia to Antimicrobial Peptides and Bacterial Survival In Vivo. J. Bacteriol.
188: 2073-2080
[Abstract] [Full Text]
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