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Thorax 2002;57:922-923; doi:10.1136/thorax.57.11.922
Copyright © 2002 BMJ Publishing Group Ltd & British Thoracic Society.
Thorax 2002;57:922-923
© 2002 Thorax

EDITORIAL

Dyspnoea

Opioids for dyspnoea

M F Muers

Department of Respiratory Medicine, Leeds General Infirmary, Leeds LS1 3EX, UK; martin.muers@leedsth.nhs.uk


Opioids have a role in the treatment of severe dyspnoea, but careful monitoring of their effects is essential.

Keywords: opioids; dyspnoea; palliation

The first 150 words of the full text of this article appear below.

To understand, define, and treat dyspnoea is difficult. It is an underappreciated problem in respiratory medicine, cardiology, and palliative medicine, and it is often hard to know when to supplement the treatment of an underlying disease by pure palliation. In this issue of Thorax Jennings et al1 present a meta-analysis of randomised controlled trials of opioids as treatment for dyspnoea, which shows that opioids do reduce dyspnoea in a variety of settings, including chronic obstructive pulmonary disease (COPD) and cancer. What inferences for clinical practice in primary care, secondary care, or specialist palliative care can be drawn from this finding? And what impact ought it to have?

BACKGROUND

Dyspnoea is a perception, and perceptions are affected by more than physiological variables. Although simple statements such as "dyspnoea is an uncomfortable sensation of breathing"2 may suffice as a shorthand definition of dyspnoea, the American Thoracic Society has suggested the following broader . . . [Full text of this article]


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  • Allen, S., Raut, S., Woollard, J., Vassallo, M. (2005). Low dose diamorphine reduces breathlessness without causing a fall in oxygen saturation in elderly patients with end-stage idiopathic pulmonary fibrosis. Palliat Med 19: 128-130 [Abstract]  

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