Management of opportunist mycobacterial infections: Joint Tuberculosis Committee guidelines 1999
Subcommittee of the Joint Tuberculosis Committee of the British Thoracic Society*
Correspondence to: Dr I A Campbell
Received 10 May 1999; Returned to author 23 July 1999; Revised version received 14 October 1999; Accepted for publication 22 November 1999
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Introduction |
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Guidelines have been produced for tuberculosis by the British Thoracic Society (BTS),1 2 the American Thoracic Society (ATS),3 the International Union Against Tuberculosis and Lung Disease,4 and the World Health Organisation.5 These, however, deal mainly with Mycobacterium tuberculosis complex infections (M tuberculosis, M africanum, and M bovis). With the exception of the ATS guidelines on non-tuberculous mycobacteria,3 these do not address the opportunist mycobacteria (also called atypical mycobacteria, mycobacteria other than tuberculosis (MOTT), non-tuberculous mycobacteria (NTM), or environmental mycobacteria).
The number of isolates of such opportunist mycobacteria has been
increasing,6 both in HIV negative and HIV positive
individuals. Because of the growing numbers of patients with disease
due to infection by these mycobacteria, the wide range of species, the difficulties in both diagnosis and management, and in response to
increasing requests for advice on management, the BTS Joint Tuberculosis Committee has reviewed the evidence on management of
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