Review series
Genetics and pulmonary medicineIntroduction
a Division of Respiratory
Medicine, City Hospital, Nottingham NG5 1PB, UK, b Osler Chest Unit, Churchill Hospital, Oxford OX3 7LJ, UK
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These are exciting times in pulmonary medicine with molecular
advances steadily providing increasing insights into the complex mechanisms of lung biology and the development of disease. These advances in knowledge will, in due course, set the scene for the development of novel modes of prevention, early and precise diagnosis, and treatment
which the pulmonologists of the future will deploy. Thorax launches today (p 389) a series of articles on one
important area of these molecular advancesgenetics. The series, as
planned, is not meant to be comprehensive but is intended instead to
illustrate some of the exciting advances and to convey how broadly
genetic factors engage pulmonary medicine. And so the series includes articles on cystic fibrosis and antitrypsin deficiency, of
course, but also articles on, for instance, inherited thrombophilia and pulmonary embolus, on the genetics of the human-microbe interaction (including the human and microbial genetics), and how these
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Genetics and pulmonary medicine
1: The genetics of cystic fibrosis lung disease
- Donald J Davidson and David J Porteous
Thorax 1998 53: 389-397.[Extract] [Full Text] [PDF]
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