REVIEW SERIES
Exacerbations in cystic fibrosis: 2 · Prevention
1 Adult Cystic Fibrosis Centre, The Prince Charles Hospital, Brisbane and School of Medicine, University of Queensland, Australia
2 Department of Respiratory Medicine, Royal Children’s Hospital, Melbourne, Australia
Correspondence to:
Correspondence to:
Dr S C Bell
Adult Cystic Fibrosis Centre, The Prince Charles Hospital, Rode Road, Chermside, Brisbane 4032, Australia; scott_bell{at}health.qld.gov.au
The life span of people with cystic fibrosis (CF) has increased dramatically over the past 50 years. Many factors have contributed to this improvement. Respiratory exacerbations of CF lung disease are associated with the need for hospitalisation and antibiotic treatment, reduction in the quality of life, fragmented sleep and mortality. A number of preventive treatment strategies have been developed to reduce the frequency and severity of respiratory exacerbations in CF including mucolytic agents, physiotherapy and exercise, antibiotics, nutritional strategies, anti-inflammatory treatments and vaccinations against common respiratory pathogens. The evidence for each of these treatments and their potential impact is discussed.
Abbreviations: CF, cystic fibrosis; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
-
Goubau, C, Wilschanski, M, Skalicka, V, Lebecque, P, Southern, K W, Sermet, I, Munck, A, Derichs, N, Middleton, P G, Hjelte, L, Padoan, R, Vasar, M, De Boeck, K
(2009). Phenotypic characterisation of patients with intermediate sweat chloride values: towards validation of the European diagnostic algorithm for cystic fibrosis. Thorax
64: 683-691
[Abstract] [Full Text] -
Jain, M., Thomson, A. H
(2009). Palivizumab, pneumococcal and influenza vaccination in cystic fibrosis. JRSM
102: 23-28
[Full Text]
- Full Text
- Full Text (PDF)
- web only appendix
- Alert me when this article is cited
- Alert me if a correction is posted
- Citation Map
Services
- Email this link to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
-
Drugs: infectious diseases
-
Cystic fibrosis
-
Vaccination / immunisation
-
Drugs: respiratory system
-
Sports and exercise medicine
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
