REVIEW SERIES

Chronic obstructive pulmonary disease c 2: Pathology and biochemistry of emphysema

J C Hogg¹, R M Senior²

¹ The University of British Columbia McDonald Research Laboratory, St Paul's Hospital, Vancouver, Canada
² Pulmonary and Critical Care Medicine, Department of Medicine, and Department of Cell Biology and Physiology, Washington University School of Medicine and Barnes-Jewish Hospital, St Louis, Missouri, USA

Correspondence to:
Correspondence to:
Professor J C Hogg, McDonald Research Laboratory, St Paul's Hospital, Vancouver, British Columbia V6Z 1Y6, Canada;
JHogg{at}mrl.ubc.ca

The pathology and pathogenesis of emphysema are reviewed, with particular reference to the proteinase-antiproteinase hypothesis.

Keywords: chronic obstructive pulmonary disease; emphysema

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