OCCASIONAL REVIEW

Central sleep apnoea syndrome in patients with chronic heart disease: a critical review of the current literature

T Köhnlein¹, T Welte¹, L B Tan², M W Elliott³

¹ Otto-von-Guericke-Universität Magdeburg, Department for Pulmonary and Intensive Care Medicine, Magdeburg, Germany
² Institute for Cardiovascular Research, University of Leeds, Leeds, UK
³ Department of Respiratory Medicine, St James's University Hospital, Leeds LS9 7TF, UK

Correspondence to:
Correspondence to:
Dr M Elliott, Department of Respiratory Medicine, St James's University Hospital, Leeds LS9 7TF, UK;
markw.elliott{at}leedsth.nhs.uk

The prevalence, prognosis, clinical presentation, pathophysiology, diagnosis, and treatment of the central sleep apnoea syndrome (CSAS) are reviewed and its relationship with congestive heart failure (CHF) is discussed. Adequately powered trials are needed with survival and health status as end points to establish whether correction of sleep related breathing abnormalities improves the outcome in patients with CHF.

Keywords: central sleep apnoea syndrome; Cheyne-Stokes respiration; congestive heart failure; periodic breathing

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